|
Symbol Name ID |
Ptgs2
prostaglandin-endoperoxide synthase 2 MGI:97798 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating antibody level |
Anemia |
Hemolytic anemia |
Eosinophilia |
Increased T cell count |
Leukopenia |
Thrombocytopenia |
Elevated erythrocyte sedimentation rate |
Hepatosplenomegaly |
| Disease(s) Associated with PTGS2 | |||||||||
| cystic fibrosis | |||||||||
| idiopathic pulmonary fibrosis | |||||||||
| pancreatic cancer | |||||||||
| rheumatoid arthritis | |||||||||
| sarcoidosis |
| Mouse Phenotypes | hematopoietic system phenotype |
abnormal osteoclast differentiation |
enlarged spleen |
spleen hyperplasia |
abnormal class switch recombination |
abnormal memory B cell differentiation |
anemia |
decreased hematocrit |
decreased platelet calcium level |
increased leukocyte cell number |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG3 level |
increased IgM level |
abnormal macrophage physiology |
abnormal platelet physiology |
increased platelet aggregation |
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| Availability | Mouse Genotype | |||||||||||||||||
| Ptgs2tm1Fun/Ptgs2tm1Fun | ||||||||||||||||||
| Ptgs2tm1Jed/Ptgs2tm1Jed | * | |||||||||||||||||
| Ptgs2tm1Unc/Ptgs2tm1Unc | ||||||||||||||||||
| Ptgs2tm3Fun/Ptgs2tm3Fun | ||||||||||||||||||
| Ptgs2tm1Unc/Ptgs2+ | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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